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Gaoy and MelodySusie highlight a growing investment in DIY tools like gel kits, lamps and drills
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Dietary choline deficiency causes DNA strand breaks and alters epigenetic marks on DNA and histones
Interestingly, frameshift mutations disrupting the C-terminal DNA binding interface of PDS5B (c.3939dup and c.3954del) have been identified in gastrointestinal cancers 37 , underscoring the possible significance of the PDS5B DNA binding attribute in tumor suppression, and indicating that cancers harboring PDS5B mutations could be targeted with PARP inhibitors 38
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