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The coordinated nature of these pathway disruptions is particularly significant, as CSCs often demonstrate remarkable plasticity and can maintain their stem-like properties through compensatory activation of alternative signaling routes when individual pathways are targeted in isolation

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In oral cancer, c-Myc also promotes cell proliferation by increasing the activity of GLS and GS, thereby improving the Gln metabolism of tumor cells

These are legitimate results for a medication that costs a fraction of what GLP-1 drugs cost

Gastroenterology 152 , 17071717 (2017)

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