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Physiology 328, F173F189
Prolonged GLP-1RAs therapy may exacerbate existing chronic inflammation in patients with T2DM, thereby potentially elevating their risk of pancreatic cancer
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IMPORTANT SAFETY INFORMATION & COMMON SIDE EFFECTS All medications have the potential for side effects
The GLP-1 receptor agonist liraglutide was able to reduce Bax expression in pancreatic cells from T2DM rats, and Bcl-2 expression was increased, islet tissue structure was improved, insulin-positive expression was increased, and -cell apoptosis was reduced (Liu et al., 2021)
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