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If sodium is below 120 mEq/L, a continuous intravenous infusion is required

It has also been reported that 5-amino-1MQ treatment requires an acclimation period, with some subjects reporting decreased exercise tolerance with cardiovascular exercise

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doi:10.1016/j.clinbiochem.2003.08.004

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The N-terminal part of the peptide hormones is essential for activation and competitive antagonists were generated by modifications or deletions of a few amino acid residues 9,10,11,12