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For instance, animal models have shown that GLP-1RAs administration reduces anxiety-like behaviors, potentially via neuromodulatory actions in brain regions such as the amygdala

Details of the prior SGLT2-i trial (dates, dose, HbA1c response) or the specific contraindication/intolerance

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The other only took the carnitine

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Exposures outside of the recommended dosage are likely similar to what would occur in clinical practice, where dosages would be prescribed on a case-by-case basis based on treatment response and tolerability