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Tackling weight loss does not have to come with the risk of drug side effects

Back Pincock, S (29 July 2006) 'Ellis Samols', The Lancet , 368/9533, 360

We need to ensure that reproductive health is part of every conversation when these drugs are prescribed to any women of childbearing age

In the liver, GCGR signaling stimulates hepatic glucose production through glycogenolysis and gluconeogenesis, promotes lipolysis, and inhibits fat accumulation

After week 24, discontinuation due to side effects dropped to just 4.2%