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Instead, the researchers were also unsure why the gap closed after an additional four weeks of study, but offered the explanations that the different groups may not have been eating enough to get the full benefit of their training, or, conversely, had overtrained

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Despite advances in antifungal monotherapy and combination strategies, critical challenges remain, such as overcoming the escalating drug resistance, optimizing individualized therapeutic regimens tailored to diverse patient populations, and improving long-term treatment efficacy to reduce recurrence and disease progression

doi: 10.1016/s0376-8716(99)00040-x

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