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Because sleep and endocrine function are closely connected, DSIP is frequently studied in relation to growth hormone regulation, cortisol activity, and neurological recovery processes

Research has demonstrated its involvement in wound healing through enhanced collagen and decorin gene expression [1] , activation of tissue remodeling pathways [2] , and regulation of genes associated with antioxidant defense and anti-inflammatory responses [3] [4]

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Therefore, it can be concluded that spirulina in doses equal 100500 mg/kg alleviate cyclophosphamide-induced cystitis and nephrotoxicity in animals (Eltantawy et al., 2018)