These include anorectic effects driven by previously discussed central modulation of satiety and reward pathways and peripheral activation of vagal afferents, delayed gastric emptying, anti-inflammatory properties, potential impact on energy expenditure and the ability to reduce ghrelin levels, which are inherently elevated in PWS ( 2 to 11.3 kg/m 2 (35), waist circumference reduction from 7 to 8 cm (32, 35), as well as HbA1c reduction from 1.9% to 6.5% (34)
Caunca MR, Odden MC, Glymour MM, et al
Br J Psychiatry (2009) 194(5):4348.10.1192/bjp.bp.108.052605 3 GroverSNebhinaniNChakrabartiSParakhPGhormodeD
Featured products Retatrutide $149.00 Original price was: $149.00.$120.00Current price is: $120.00
In fact, the only study that I could find involving humans was a very small retrospective study with just 16 participants
doi: 10.1016/0923-2508(93)90217-P 67 CustodioR.JohnsonE.LiuG.TangC