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Pre-requisites- -

Fish and chips, corn dogs, fried mozzarella sticks, tempura, and deep-fried anything should move to the "not right now" list for the duration of your tirzepatide protocol

Pain intensity significantly improved from baseline to month 1 of treatment (pain NRS from 7.4 1.5 to 5.6 1.7)

Small observational studies in patients with type 2 diabetes have reported improvements in neuropathic pain scores after GLP-1 initiation

PlexusDx Microdose GLP-1 Protocol ($129/mo) offers gentler entry if starting full-strength tirzepatide feels too aggressive

Research suggests semaglutide may have enhanced ability to cross the blood-brain barrier compared to liraglutide, leading to stronger effects on the hypothalamic appetite centers