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To unequivocally confirm the proposed structure of the ethyl ester of the tetradepsipeptide ( m/z 453.2576) and the octadepsipeptide ( m/z 837.4806), respectively, in a first set of experiments cell pellets of strain F3876/87 were extracted with MeOH or MeCN/H 2 O (70/30, v/v) instead of EtOH and the extract was analyzed for depsipeptide methyl esters as well as the free depsipeptides by UPLC-TOF MS

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However, in healthy resistance-trained individuals, the muscle-building effect may be modest compared to structured strength training and adequate nutrition