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This is thought to result from enhanced satiety signaling in the brain, particularly in the hypothalamus, where these gut hormone pathways converge to regulate hunger

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Flow cytometry analysis revealed a significant decrease in the proportion of M1 macrophages and a concurrent increase in the M2 macrophage population in the GLP-1RAs@NPs-WYRGRL group compared to both the LPS group and the NPs-WYRGRL group (Fig

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