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Interestingly, while we do not know the role of GLP-1 in this circuit on food reward several studies have explored the therapeutic potential of nigro-striatal GLP-1 action in animal models of Parkinson's disease (Harkavyi et al., 2009

Potential side effects may include: Nausea Stomach discomfort Mild diarrhea These effects are usually temporary and improve with dosage adjustments

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It is a secondary release, STAT dependent IFN (Chambers, 2022)