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Free radical biology and medicine

It is intended for scientific research only and must be handled in certified laboratory environments.

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Diabetic cardiovascular disease induced by oxidative stress

We also summarize newly proposed mechanisms associated with hepatoprotection and tumor suppression, such as attenuation of hepatocellular stress through inhibition of the NEDD9/FAK/AKT cascade and a potential role in cell-cycle regulation via the HDAC/p21 axisalthough the latter remains to be validated in MASLD-specific models

Phase 1b (2021) Enebo and colleagues published a randomized, placebo-controlled, multiple-ascending-dose Phase 1b trial in The Lancet in 2021 [3]