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Practices using multi-touch reminders see 10-15% improvement in show rates
Addressing Common Absorption Barriers Things like stomach problems, some meds, and getting older can make it hard to absorb vitamin B12
counsel on vomiting-related missed doses | | Levothyroxine | Cmax reduced ~16% | Recheck TSH at 6 to 8 weeks | | Digoxin | Tmax delayed 2.5 hours, Cmax reduced 17% | Check trough level at 5 to 7 days | | Metformin | Cmax reduced 9%, AUC unchanged | No adjustment | | Statins | Cmax reduced up to 38%, AUC unchanged | No adjustment | | ACE inhibitors/ARBs | Cmax reduced ~15%, AUC unchanged | No adjustment | | DPP-4 inhibitors | Pharmacologic redundancy | Discontinue DPP-4i | | SGLT2 inhibitors | Additive efficacy, no PK interaction | No adjustment | | DOACs | No data
By subcutaneous injection (Wegovy): initially 0.25 mg once a week and increased every 4 weeks until the full dose of 2.4 mg is reached
ERR co-activation PGC-1alpha binds ERRs (primarily ERRalpha in muscle), dramatically amplifying their transcriptional activity on genomic ERREs
The FDAs move on BPC-157 isnt the end of the world, but its also not nothing
