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11(3): 27-47 URL: DOI: Depression is a neuropsychiatric disorder that has in recent times become a leading cause of disability and a major contributor to global disease burden and suicide[1]

CO has well recognized protective effects in models associated with oxidative stress [32] and is a known inducer of GCL [33]

With a half-life of only 13 hours, liraglutide creates a much more pronounced peak-and-trough pattern within each 24-hour period

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Based on these mechanisms, emerging interventional strategies have been proposed to curb intercellular ferroptotic spread, including: blocking exosome-mediated signal transmission, inhibiting STING pathway activation, and enhancing astrocytic phagocytic and clearance functions

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