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In the United States, the FDA categorizes glutathione as "Generally Recognized as Safe" (GRAS) for the general population

3.1 Biological Interpretation of GSH and GSSG Concentrations A decrease in GSH can result from reduced synthesis, oxidation, conjugation, protein S-glutathionylation, export, degradation, or loss of cellular integrity

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The 100 mL volume water bath consisted of a simple heating set up, in which a 500 mL glass beaker from VWR was filled and placed on a hot plate

For more information on the Hospital OQR Program, we refer readers to section XV

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