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They may achieve this by altering biological pathways and genetic susceptibility, 23,84,85,86 making it challenging to pinpoint a direct cause of clinical pathology in AD

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d , Lysates from HEK293T cells transfected with Flag-tagged NMHC-IIA Coiled coil (CC) domain (IIA-CC-Flag) and HA-tagged N and C terminal fragments of TMEFF1 were subjected to IP with anti-HA, and immunoblotted as indicated

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