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It has shown efficacy in animal models of inflammatory bowel disease (IBD), gastric ulcers, and "leaky gut." Systemic anti-inflammatory effects: It appears to dampen inflammatory cascades without the immune-suppressing risks associated with corticosteroids

Furthermore, challenges such as low drug concentration at the local pathological site after systemic administration, limited target specificity and short drug half-life persist [6]

When gut microbiome composition shifts, it can reduce the protective bacterial populations that serve as the first line of defense against urinary pathogens

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