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Mateus, F., Moreira, S., Martins, A., Oliveira, P., Alves, M., & Pereira, M

Notably, compound 6 (Figure 9), a highly selective COX-2 inhibitor (IC 50 = 0.04 M, SI = 337.5), showed superior results in reducing ROS and NO production compared to celecoxib

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Ipamorelin Ipamorelin (Ala-His-D-2-Nal-D-Phe-Lys-NH2) is a pentapeptide designed to be a selective growth hormone secretagogue

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GLP-1, produced in enteroendocrine L-cells and preproglucagon neurons in the NTS, plays a central coordinating role by integrating peripheral and central signals, then modulating downstream pathways that control appetite, metabolism, and behavior [9,34]