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Recruited originally to help improve laundry detergent enzymes to make clothes look brighter, Knudsen soon got drawn into a small team set up in 1990 by Ole Kirk, an organic chemist and physician, to discover new peptide candidates to treat type 2 diabetes (Molteni, Chen

In clinical trials, people lost an average of 9.4% to 14.7% of their body weight over 40 weeks

The thought is that the GLP-1 agonists mechanism of action can lead to pancreatic cell hyperplasia (since the GLP-1 receptors are in the islet beta cells and exocrine duct cells), leading to a back up in pressureand you got it, inflammation

Toft-Nielsen, M.-B

Hofso, D

These observations suggest that monotreme GLP-1 peptides may have gained new as yet undefined functions