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Whereas first-generation vaccines rely mainly on spike, there is strong evidence that adaptive immunity to nonspike antigens contributes to protection from infection and disease in natural infection

3 Gut (2011) Randomised placebo-controlled trial of teduglutide in reducing parenteral nutrition and/or intravenous fluid requirements in short bowel syndromeThe earlier phase 3 dose-ranging study (PMID 21317170), n=83

The pathway governs cytoskeletal reorganization, anchoring repair cells to damaged tissue

Bana P, rknyi R, Lvei K, Lak , Trs GI, les J, Faigl F, Greiner I (2017) The route from problem to solution in multistep continuous flow synthesis of pharmaceutical compounds