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These differences can be attributed to methodological variations (the use of 7T spectra, more dorsal voxel placement in our study) as well as notable differences in the clinical samples (the use of injectables and the inclusion of both inpatients and outpatients, and the exclusion of patients with low adherence in our study)

10.1016/j.bbabio.2010.04.018 116 PangrazziL.BalascoL.BozziY

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112 Interestingly, p53 regulates autophagy in a dual manner, where the pool of nuclear p53 protein promotes autophagy through a transcription-dependent process