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To assess the effect of these manipulations, we monitored the loss of membrane integrity under conditions of ferroptosis induction

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Given that glutamate is a critical nitrogen donor for transamination reactions that generate most NEAAs, limited availability of glutamate in NRF2-addicted cancer cells results in increased dependency on exogenous NEAAs (LeBoeuf et al

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[DOI] [PubMed] [Google Scholar] 15.Spiering BA, Kraemer WJ, Hatfield DL, Vingren JL, Fragala MS, Ho JY, Thomas GA, Hkkinen K, Volek JS