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You need branded GLP-1s or insurance coverage

Typical dosages may involve taking one or two tablets daily, usually with meals, to ensure optimal absorption and reduce the risk of gastrointestinal side effects

It wasnt until the success of GLP-1 medications for diabetes in 2005 and, later, obesity in 2021 that peptides became a major focus of the pharmaceutical industry, Kates said

We do not know the optimal human dosing, long-term safety profile in humans, or whether animal results translate directly to human outcomes

The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health