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Drug-Induced Liver Injury (DILI) Liver is the main target organ of drug toxicity, because it acts a crucial part in human drug metabolism and clearance

however, loss of function mutations in HSL cause FLD in humans (142) and partial lipodystrophy with age (204, 205)

In the U.S., it's lumped in with dietary supplements, not meds, so the FDA doesnt really oversee the details

Its FDA approval provides regulatory advantage and its targeted mechanism provides unique research opportunities

How do we determine if a company has high operating leverage

Supplementation with synbiotic kefir (goat milk kefir with probiotics) in high-fat, high-fructose (HFHF) diet-fed rats lowered HbA1c levels, improved insulin production, and enhanced overall metabolic health compared with non-supplemented kefir (Nurliyani et al., 2022)