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Le temps ncessaire pour ressentir une amlioration varie selon les personnes et leur mode de vie
A propensity-matching approach might have yielded more balanced study groups and increased the internal validity of the findings
However, discontinuing the medication entirely often leads to weight regain because GLP-1s address physiological drivers of hunger and metabolism that persist even after weight loss
Only four clinical studies specifically examined GLP-1RAs in mood disorders (Table 4)
It cites a 2015 meta-analysis of 14 randomised controlled trials finding consistent but modest HbA1c reductions, while noting many trials lacked rigorous controls and that publication bias toward positive findings is likely
