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The main published Phase 2 obesity study looked at retatrutide in adults with obesity, or overweight with at least one weight-related condition

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This triple mechanism explains why clinical trials showed weight loss results exceeding all previous medications in this class

Moreover, the magnitude of WL with retatrutide also exceeded that seen with other pipeline multi-agonists such as CagriSema (cagrilintide, an amylin agonist, in combination with semaglutide), mazdutide and survodutide (Fig