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Notably, FX simultaneously activates both AMPK and the Nrf2 signaling pathway, orchestrating coordinated redox homeostasis remodeling and inflammatory microenvironment regulation via suppression of the TLR4/MyD88/NF- B cascade, ultimately reducing TNF-/IL-6 secretion (Mumu et al., 2022

doi: 10.3748/wjg.v11.i21.3222 133 LeeKHChoiEYKimMKKimKOJangBIKimSWet al

The chemical structure of these medications depends on stable conditions to preserve the amino acid chains that give them therapeutic power

Within the TME, cancer cells must counteract oxidative stress and maintain intracellular redox homeostasis

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