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BMPs regulate NSC differentiation into astrocytes by acting through the phosphorylation of Smad proteins 1, 5, and 8, which combine with Smad4 in order to form a complex that translocates to the nucleus and regulates gene transcription (Itoh et al., 2000

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In photoactive systems, cytotoxic activity depends strictly on light irradiation, restricting their use to specific clinical contexts

[DOI] [PubMed] [Google Scholar] 5.Jeschke V., Kearney E.E., Schramm K., Kunert G., Shekhov A., Jonathan Gershenzon J., Vasso D.G