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A number of other factors may deplete glutathione levels including: UV radiation Viral infections such as hepatitis Household chemicals Heavy metals Environmental toxins Surgery Inflammation Septic shock Burns Dietary deficiencies of enzyme cofactors or glutathione precursors Liver cirrhosis Acute or chronic alcohol intake Some pharmaceutical drugs Some pulmonary diseases Six quick glutathione facts Regular exercise increases glutathione levels 23

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Vincenzi, P., Francia, G., Dorizi, R., Predrazzoli, R

Kinetics and redox regulation of Gpx1, an atypical 2-Cys peroxiredoxin, in Saccharomyces cerevisiae

Journal of Clinical Medicine , 2021 Because of this, any long-term use beyond 68 weeks is based entirely on user experimentation and not medical data