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A large number of growth factors and their activated signal transduction pathways are known to provoke the loss of E-cadherin function and induce cancer cell migration and invasion [16]

Regarding choice of comparison group, it is noteworthy that inverse associations between GLP-1RA use and prostate cancer risk have been found in studies using different comparator drugs, i.e

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Meanwhile, DAG might activate protein kinase C (PKC)