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Research suggests it may influence fibroblast activity and extracellular matrix synthesis, though clinical applications remain exploratory

Reference: FOXO4-DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53-serine 15 phosphorylation

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Cancer Cell 16 , 401412 (2009)

[DOI] [PMC free article] [PubMed] [Google Scholar] 50.Angrisani L., Santonicola A., Iovino P., Vitiello A., Higa K., Himpens J., Buchwald H., Scopinaro N