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Establishment of Diabetic Neuropathic Pain Model and Drug Treatment We used a single intraperitoneal injection of freshly prepared STZ at a dosage of 60 mg/kg body weight in 0.01 M of the citrate buffer, pH 4.5, to induce diabetes

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Clinical trials demonstrate that GLP-1 therapy reduces fasting insulin levels by 30-40% in many patients, even before significant weight loss occurs