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Providers can assess whether symptoms reflect expected medication side effects, true allergic reaction, or an underlying condition requiring different treatment

Abnormal mitochondrial metabolism of immune cells has been reported in autoimmune diseases, such as rheumatoid arthritis (RA) (19) and systemic lupus erythematosus (SLE) (20)

NHS B12 injections are prescribed for documented deficiency or malabsorption conditions including pernicious anaemia, gastrointestinal disorders affecting absorption, previous gastric surgery, and when neurological symptoms are present

Such inflammatory cytokines may either cross the blood-brain-barrier, especially if it is damaged, or be produced in situ by reactive astrocytes and microglia (137)

Coenzyme Q10 significantly decreased bipolar depression severity without changing creatine kinase activity [63]

Anyone using these compounds should work with a clinician and start low