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the NIHR Imperial Biomedical Research Centre

Limited long-term data: Most published studies span weeks to months

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For antimicrobial protection, avoid rubber closures, which can allow contamination through the hole where the needle passes, and may contain rubber additives

It seems, however, that while stimulation of some GLP-1R expressing neuronal populations is responsible for reducing food intake in association with nausea or aversion stimulation of others can lead to food intake reduction via mechanisms independent of nausea (McMahon and Wellman, 1998

People not generally eligible for GLP-1s at higher doses