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Yang WS, SriRamaratnam R, Welsch ME, Shimada K, Skouta R, Viswanathan VS, et al

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A 2015 Pharmaceutical Research study confirmed this: after microneedle treatment, 134 nmol of peptide and 705 nmol of copper permeated through skin over 9 hours

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The current FDA position on these peptides certainly puts a greater burden on consumers