The FDA cited the lack of human studies on the peptide and concerns about safety as its rationale
M., English, J., Aitchison, T
We describe prescribing volumes and patient characteristics over time, by medication, and by FDA-labeled use (e.g., use as anti-diabetic medication (ADM), an anti-obesity medication (AOM), or unknown)
Pathophysiology: The biological basis for disease in adults and children (8th ed.)
Clinical trials show average weight loss of 15-20% of body weight over 68 weeks with semaglutide (Wegovy) and 15-22% with tirzepatide (Zepbound)
The MHRA is urging individuals in the UK who are on GLP-1 medicine and have been hospitalized due to acute pancreatitis to submit a report to its Yellow Card scheme