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In the mechanism study, Ex-4 treatment significantly increased the expression of GLP-1R, p-AMPK, IB-, Occludin, and Claudin-5, while the expression of p-nuclear factor-kappa B (NF-B) p65, matrix metalloproteinase-9 (MMP-9), and albumin was significantly decreased

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2026 Feb 8;27(4):1651

Frequently Asked Questions Can GLP-1 injections like semaglutide actually cause gastroparesis

Rats were housed individually during the treatment and maintained access to their assigned diet