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It regulates cortisol/corticosterone release and interacts bidirectionally with sleep systemsstress disrupts sleep, and poor sleep activates stress responses

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For glycemic control in type 2 diabetes, treatment is typically continued indefinitely as long as it remains effective and well-tolerated, with periodic assessment of the ongoing need for therapy

doi: 10.1111/jre.12912 147 WeisbergSPMcCannDDesaiMRosenbaumMLeibelRLFerranteAWJr.Obesity is associated with macrophage accumulation in adipose tissue

Intrinsic and antipsychotic drug-induced metabolic dysfunction in schizophrenia