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Astrocytes in motor neuron diseases

Mitochondrial sirtuin 3 (SIRT3) is a major modulator of mitochondrial metabolism and homeostasis, regulating UPR mt , mitochondrial biogenesis, mitophagy, fusion/fission, and antioxidant expression 98

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One study looking at the impact of the GST polymorphisms on the relationship between omega 3 fatty acids and breast cancer risk found an increased protective effect of dietary intake of fish omega-3 fatty acids in the women with the genetic polymorphisms for reduced GST activity

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