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Mashimo, H., Kjellin, A

Long enough for most structural changes to return to baseline but short enough to maintain protocol feasibility

These observations suggest that either the loss of homology and/or introduction of new epitope content in peptide impurities can lead to increased immune responses (movement to the left or toward the top of the quadrant plot) compared to the parent API peptide

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& Lindgren, C

That might mean that the melatonin one picks up in the pharmacy doesn't have the same ingredients in it that the bottle listed