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The redox-active sulphydryl group of GSH can protect cells from ROS by directly scavenging free radicals and acting as a cofactor for antioxidant enzymes such as glutathione peroxidases (Gpx1p, Gpx2p and Gpx3p)

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In particular, four significant potential dangers of B12 replacement should be highlighted: severe hypokalemia , thrombocytosis, cardiovascular complications , and neurological symptoms such as numbness, tingling, or joint pain

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