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J Clin Invest 103: 239251, 1999 [DOI] [PMC free article] [PubMed] [Google Scholar] 53.Schutte R, Schutte AE, Huisman HW, van Rooyen JM, Malan NT, Pter S, Fourie CM, van der Westhuizen FH, Louw R, Botha CA, and Malan L

Polyphenols have been shown to beneficially alter the gut microbial composition by encouraging the proliferation of commensal bacteria and suppressing pathogenic strains

The trial did not meet its efficacy endpoint, but tolerability was not the reason the program was discontinued

Paying attention to changes in the gut microbiota derivative TMAO, we have to pay attention to the gut microbiota

Sources: Pickart L, et al