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Two active forms of GLP-1 are generated in the gut and brain: active GLP-1 (7-36) amide and active GLP-1 (7-37) non-amide 10

Bibcode:2017JBiCh.292.7131K

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The nausea model achieved a receiver operating characteristic area under the curve of 65.4% in the test set, whereas the vomiting model achieved a receiver operating characteristic area under the curve of 68.0% (Fig

Engineering bimodal molecules that integrate GLP-1R agonism with specific pain-related mechanisms may offer innovative therapeutic options