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Comorbidity with allergic and autoimmune disorders such as atopic eczema, allergic rhinitis and asthma is another factor that could increase the risk for ADHD and future research may lead to a better understanding of the mechanisms underlying the observed comorbidity [38,42,43,44]

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For those dealing with systemic inflammatory conditions that manifest across multiple organs, KPV's mechanism is relevant beyond the gastrointestinal tract

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The reduced form of Glutathione, known as GSH, is the biologically active form studied in most research contexts, and its ratio to oxidized Glutathione serves as a key marker of cellular redox status in laboratory models

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Iron also mediates the downregulation of E-cadherin, a hallmark of EMT (Brookes et al., 2008)

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Moreover, the traditional anticancer treatments are responsible for compromised lifestyle of the patient and they have significant side effects [1, 2]

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J.PerezG.et al

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