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Overall, bees are not repelled by azadirachtin, and they may collect contaminated food during foraging, leading to adverse sublethal effects after ingestion (Naiara Gomes et al., 2020)

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Altun T, Jindal S, Greenseid K, et al

ALDH2 deficiency dramatically slows acetaldehyde conversion, producing toxic accumulation symptoms

At very high doses, some horses may show reduced feed acceptance due to the strong odor or taste

It is now clear, however, that paracetamol acts via (at least) two pathways.[6][7][8][9] The COX family of enzymes are responsible for the metabolism of arachidonic acid to prostaglandin H2, an unstable molecule, which is, in turn, converted to numerous other pro-inflammatory compounds