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They also found a significant reduction in fasting plasma glucose, serum insulin levels, homoeostasis model of assessment-insulin resistance and dehydroepiandrosterone sulphate (DHEAS) in the treated patients

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For menopausal women, tirzepatide may have an edge over semaglutide because GIP receptors are found in adipose tissue and may directly influence fat metabolism beyond what GLP-1 alone can achieve

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