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(PubMed) Madigan SM, Tracey F, McNulty H, et al

Acidic pH is a metabolic switch for 2-hydroxyglutarate generation and signaling

However, much of the evidence linking IF-induced lysosomal activation to improved clinical outcomes is derived from animal studies or in vitro models [34]

10.1111/j.1440-1681.2008.04906.x 95 PisarchikA.SlominskiA