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Metformin, a drug widely used in the treatment of diabetes, has been found to exert its antidiabetic effects by changing the gut microbiota, partially restoring the gut dysbiosis associated with T2DM 184

For recordings during free-moving feeding, mice either food-deprived for 24 hours or fed normally were introduced to a transparent acrylic enclosure measuring 15 15 30 cm and then connected to the fiber photometry apparatus

[9] [10] The proposed mechanism centers on the gut microbiome's role in metabolic regulation

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